Flutamide, a pure antagonist of the androgen receptor, is effective in the treatment of acne in women. It has generally been found to reduce symptoms of acne by 80 or 90% even at low doses, with several studies showing complete acne clearance. In one study, flutamide decreased acne scores by 80% within 3 months, whereas spironolactone decreased symptoms by only 40% in the same time period. In a large long-term study, 97% of women reported satisfaction with the control of their acne with flutamide. Although effective, flutamide has a risk of serious liver toxicity, and cases of death in women taking even low doses of the medication to treat androgen-dependent skin and hair conditions have occurred. As such, the use of flutamide for acne has become increasingly limited, and it has been argued that continued use of flutamide for such purposes is unethical. Bicalutamide, a pure androgen receptor antagonist with the same mechanism as flutamide and with comparable or superior antiandrogenic efficacy but without its risk of liver toxicity, is a potential alternative to flutamide in the treatment of androgen-dependent skin and hair conditions in women.
Low concentrations of salicylic acid, like 0.5 percent, are perfect for people who have both acne and sensitive skin. If you have sensitive skin, you know that most of the “best” acne medications just don’t work for you because they are too strong. Products that are too strong for you can cause increased inflammation, which can actually lead to more acne rather than less. Because of this, salicylic acid is our number one recommendation for sensitive skin.
Acne isn’t just a problem for teens. According to studies, those pesky zits and pimples can pop up at any age. Whether it’s your diet, environment or stress that’s to blame, you don’t have to suffer helplessly. To get the skinny on acne, we talked to board-certified dermatologist Cynthia Bailey, M.D., president and CEO of Advanced Skin Care and Dermatology Physicians, Inc. and founder of DrBaileySkinCare.com. Here, she shares her best tips on how to choose the right acne cleanser for you, as well as how to use it to get the best results.
The Daily Skin Clearing Treatment is an all-over 2.5 percent benzoyl peroxide cream that also touts calming bisabolol and allantoin to alleviate the dryness and irritation that can crop up mid-treatment. Anyone frustrated with oil-slick skin will also love this part of the regimen — it creates a satin mattifying effect, instantly transforming shininess into a glow.
Combination therapy—using medications of different classes together, each with a different mechanism of action—has been demonstrated to be a more efficacious approach to acne treatment than monotherapy. The use of topical benzoyl peroxide and antibiotics together has been shown to be more effective than antibiotics alone. Similarly, using a topical retinoid with an antibiotic clears acne lesions faster than the use of antibiotics alone. Frequently used combinations include the following: antibiotic and benzoyl peroxide, antibiotic and topical retinoid, or topical retinoid and benzoyl peroxide. The pairing of benzoyl peroxide with a retinoid is preferred over the combination of a topical antibiotic with a retinoid since both regimens are effective but benzoyl peroxide does not lead to antibiotic resistance.
But the side effects of targeted breakout cream treatments aren’t always worth it. “So many products instruct consumers to use benzoyl peroxide spot treat red bumps and pustules. I don’t recommend it,” says Dr. Lawrence Green, board-certified dermatologist and assistant clinical professor of dermatology at George Washington University. Such high concentrations of benzoyl peroxide cause added irritation and inflammation to already sensitive skin, so with this in mind, we cut kits that included spot treatments.
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Aside from adding bacteria to your skin, these forms of contact can irritate the skin, adding to the appearance of redness and causing increased inflammation. In the event that your pimples get ruptured during this process, the oil and bacteria that was trapped inside could spread to the surrounding skin on your face, which causes acne to spread. So, not only will rubbing, squeezing and scratching leave your acne-ridden skin further irritated, it will increase the amount of acne you will have to deal with.
This is a tip that I personally treasure so I can only imagine how valuable it will be for men. For years, shaving used to be a real hit and miss kind of deal for me. Sometimes I used to have a perfect shave, and other times my skin would be left raw and irritated. At first, I thought it was the razor blades that were the issue. I thought that perhaps it was the fact that the blades were getting dull or that they were nicked. It got to the point that I started using a different blade every time I shaved!! Not exactly practical or financially economically, I know. 😉
You’ll need to practice patience with acne treatments that contain tretinoin, but many users say the wait is worth it, considering the results. Generally, it takes up to six months, but often less, to notice results from tretinoin. Note: you may experience a slight increase in acne in the first couple of weeks of use, but it’s only temporary as your body adjusts to the medicine.
If you’re used to seeing advertisements for acne treatments using five or six different products to clear up blemishes, you might be surprised that a simple three-step kit is our top pick. In fact, we favored Paula’s Choice for its simplicity. This twice-daily, three-step kit — which includes a cleanser, an anti-redness exfoliant, and a leave-on treatment — is concise without cutting corners.
Stronger cases may call for prescription retinoids (such as Retin-A or Tazorac), which “are really the standard of care for most acne therapy,” says Joshua Zeichner, MD, director of cosmetic and clinical research in dermatology at Mount Sinai Hospital in New York City. Certain drugs, such as Epiduo and Ziana, combine retinoids with antibacterials and may be more effective than separate products. Because retinoids also have anti-wrinkle properties (they help stimulate collagen production), they are especially beneficial for adult acne sufferers.
Dr. Ellen Turner and her team provide treatment for skin conditions, including eczema, psoriasis, rosacea, acne, moles, and more in Dallas, Irving, and Cleburne; as well as Plano, Arlington, and beyond. Cosmetic options include Botox®, Juvéderm®, Restylane®, Perlane®, Ultherapy®, Fraxel®, IPL, laser hair removal, laser resurfacing, and CoolSculpting®.
Perhaps one of the most popular cleansers for combination skin care on the market today, Boscia's purifying cleansing gel works best for oily to normal skin types. It works by gently cleansing skin without stripping it and adding harsh elements to the skin. It can be a tad drying, so it works best on women with more oily spots than dry spots. You can also use it to cleanse your oily T-zone, but keep it away from your dry spots, where you may want to moisturize more.
This dermatologist-tested formula is a foaming face wash that works incredibly fast. It can make skin visibly clearer in as little as 12 hours. It’s made with 2% salicylic acid, Acceladerm Technology™, and PHAs, polyhydroxy acids that open pores, improve skin moisturization and calms the skin. It unblocks pores, kills bacteria and calms and soothes the skin. This Clearasil product is guaranteed to be so good that if it doesn’t work for you, they have a 30-day money-back guarantee that you can take them up on.
Although immediate results would be great, acne treatment does not occur overnight. It is a process that requires follow-up appointments to determine and adjust your treatments to your particular skin type. Expect six to 12 weeks for results. While waiting for an acne treatment to work, it can be tempting to squeeze lesions to get rid of them. Dermatologists do not recommend this. Picking, scratching, popping and squeezing tend to make the lesions worse and can cause acne scars.
Protect your skin. Skin care doesn't end when you leave your bathroom. Wear a noncomedogenic (non-pore clogging) sunscreen with an SPF of 30 or more that offers both UVA and UVB protection to shield your sensitive skin against the sun's harsh rays. A water- or light liquid-based sunscreen is best for acne-prone skin. Limit your time in the sun, especially between the hours of 10 a.m. and 2 p.m. While outside, wear a hat with at least a 2-inch brim and clothing to cover exposed skin.
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Try not to sweat. Wash at least twice a day, sweating only increases acne. Properly use a cleanser. Wash your face with cool water and apply a little on your fingers. Gently massage the product into the skin with slight massage movements, then wash several times thoroughly. Do not use a sponge under any circumstances; this will only increase irritation. Pay attention not only to the face but to other parts of the bode that are prone to acne.
Accutane is especially good for cystic acne in women and body acne in men. “Oral vitamin A basically shuts down your sebaceous glands. If you suppress [them] for a long enough period, you can cure someone of their acne, and about 50 percent do hit that cure rate,” says Linkner. A course of Accutane can take about six to nine months. Sometimes patients need to repeat the course at a higher dosage in order to truly eliminate acne.
Whether it’s just or not, you are judged by your appearance: the clothes you wear, your hairstyle, your body language. And if you have acne, life can be more difficult for you. You may feel uncomfortable in social settings. You may lose your confidence. It could destroy intimacy with someone you care about. If your poor self-esteem affects your job performance, then having acne could even have a negative impact on your income and career advancement. There’s no such thing as ‘growing out of acne’. It’s an issue that needs to be taken seriously. The only way to fight acne is by treating it. And to fight acne head-on, you need to find the best acne treatment for you.
Spironolactone has relatively minor side effects, like low appetite, weakness, or cramping, but there’s one major exception: spironolactone comes with a black box warning about its cancer-causing effects. The FDA is required to include this label based on a study conducted in the 1950s that found carcinogenic properties in the spironolactone given to rats in an experiment. However, the dose of spironolactone used in this study was nearly 500 times higher than the dose currently prescribed, and no studies since have found anything carcinogenic about spironolactone. Because of this, most dermatologists feel comfortable prescribing spironolactone for acne. Still, it’s something to be aware of before you take it. Additionally, those with low blood pressure or kidney conditions are likely not good candidates for spironolactone and may want to explore other acne treatment options.
Acne treatments come with different ingredients and formulas, but our method for choosing the best acne products is hardly top-secret. As with all of our “best of” reviews, we looked for products that have plenty of positive reviews and a strong track record of delivering proven results over time. We ignore products that promise a quick-fix or aren’t backed by sound science. We like products with natural ingredients, but that didn’t determine our final choices. We think you’ll be well-served by the products listed here.
While a few people suffer from acne that is so severe it requires a medical prescription from a doctor, most people with mild to medium acne problems can find decent over-the-counter treatments that really work. The first key to getting your acne cleanser right is to know what active ingredients combat your acne, and then finding an acne treatment that contains it. Here are a few of the ingredients you want to look for:
Acrokeratosis paraneoplastica of Bazex Acroosteolysis Bubble hair deformity Disseminate and recurrent infundibulofolliculitis Erosive pustular dermatitis of the scalp Erythromelanosis follicularis faciei et colli Hair casts Hair follicle nevus Intermittent hair–follicle dystrophy Keratosis pilaris atropicans Kinking hair Koenen's tumor Lichen planopilaris Lichen spinulosus Loose anagen syndrome Menkes kinky hair syndrome Monilethrix Parakeratosis pustulosa Pili (Pili annulati Pili bifurcati Pili multigemini Pili pseudoannulati Pili torti) Pityriasis amiantacea Plica neuropathica Poliosis Rubinstein–Taybi syndrome Setleis syndrome Traumatic anserine folliculosis Trichomegaly Trichomycosis axillaris Trichorrhexis (Trichorrhexis invaginata Trichorrhexis nodosa) Trichostasis spinulosa Uncombable hair syndrome Wooly hair Wooly hair nevus