What it is: Originally under the brand name "Accutane" but now available only in generic form, isotretinoin is a derivative of vitamin A taken in pill form for 15-20 weeks. Doctors normally prescribe it for people with "severe nodular acne" that does not respond to other treatments. Nodules are inflammatory lesions with a diameter of 5mm or more. A single course of 15-20 weeks has been shown to result in complete clearing and long-term remission of acne in many people.1-2 Learn more on the Accutane page of acne.org.
In one 2018 meta-analysis published in the Journal of the European Academy of Dermatology and Venereolog, researchers found that milk consumption—particularly skim milk, which is higher in sugar than whole milk—was associated with a greater risk of acne. Beyond the higher sugar content, scientists believe that proteins and hormones found in milk products, including IGF-1, may play a role in acne flare-ups by increasing oil production and inflammation.
Salicylic acid is a topically applied beta-hydroxy acid that stops bacteria from reproducing and has keratolytic properties.[132][133] It opens obstructed skin pores and promotes shedding of epithelial skin cells.[132] Salicylic acid is known to be less effective than retinoid therapy.[19] Dry skin is the most commonly seen side effect with topical application, though darkening of the skin has been observed in individuals with darker skin types.[1]

Also, refrain from moisturizing as you’ll want your face clear of even beneficial elements. Then, in the morning, gently press the blotting paper to the different areas of the face that you want to check. Don’t rub your skin with the paper as this will cause irritation, so instead just blot. The result will be that you’ll be able to see the amount of oil that is present in the different areas of your skin.


Oral antibiotics are the standard of care in managing acne that is moderate to severe, resistant to topical therapy and covers large body surface areas. Oral antibiotics that may be prescribed to treat acne include tetracycline, doxycycline, minocycline, erythromycin, trimethoprim-sulfamethoxazole, trimethoprim and azithromycin. Combination therapy (the use of two or more therapies) including oral antibiotics and topical medication (often retinoids) may help treat acne.
For adult women, spironolactone is preferred over oral antibiotics since women with adult acne will likely have this condition at least until menopause, and starting and stopping an oral antibiotic over many years could potentially contribute to drug resistance and decreased microbial response. Spironolactone is completely safe to use on an ongoing basis once the correct dose is determined by the treating physician. It is advisable to check a potassium level at the 150mg dosing.
Social Security number: If you chose to apply for credit, allowing you to make your payment by invoice, you may be required to provide your social security number on our website. Your social security number will be directly transferred and available only to our payment service provider, which will process your social security number to be able to obtain a credit report and to facilitate your payment. The legal basis is that the processing is necessary for us to ensure accurate identification of our customers for invoice purposes and to fulfill our contractual obligations to you under the purchase agreement. It is our policy to retain your social security number only as long as reasonably necessary for this purpose.

Oral contraceptives can help normalize hormonal surges and regulate monthly cycles so that oil glands don’t go into overdrive, says Dr. Zeichner. Doctors may prescribe one of four brands of birth control pills—Yaz, Beyaz, Estrostep, and Ortho Tri-Cyclen—that are FDA approved for treating acne. As always, patients taking oral contraceptives should be aware of potential birth control side effects, including blood clots or vaginal dryness.
For example, if you have acne on dry skin, you need something gentle enough to cleanse and exfoliate but not dehydrate, like a Neutrogena cleanser. If you have oily skin, you’re looking to exfoliate and combat oil production with a product like Cetaphil. If you have combination skin, you need something that can treat your unique skin and balance it out, like Exposed Skin Care.

Social Security number: If you chose to apply for credit, allowing you to make your payment by invoice, you may be required to provide your social security number on our website. Your social security number will be directly transferred and available only to our payment service provider, which will process your social security number to be able to obtain a credit report and to facilitate your payment. The legal basis is that the processing is necessary for us to ensure accurate identification of our customers for invoice purposes and to fulfill our contractual obligations to you under the purchase agreement. It is our policy to retain your social security number only as long as reasonably necessary for this purpose.
×