Contrary to the marketing promises of “blemish banishers” and “zit zappers,” immediate results are not the trademark of acne treatments — a frustrating truth to anyone suffering through a breakout. And while pimples are personal (your stress-induced spots will look and act differently than your best friend’s breakout), the best acne treatments will include a regimen of products to hit all of acne’s root causes. We tested 43 kits to find the most well-rounded breakout-fighting solutions on the market.
The cleanser and powerful acne treatment in a single formula are designed to treat and prevent breakouts in just one easy step. It’s a deep-cleaning, oil-free formula for cleansing deep into your pores to help anyone, with any skin type, get rid of acne. With only 2% salicylic acid, this gentle formula has special skin soothers that help prevent irritation and over-drying, leaving your skin feeling soft and smooth without the oiliness.

Low concentrations of salicylic acid, like 0.5 percent, are perfect for people who have both acne and sensitive skin. If you have sensitive skin, you know that most of the “best” acne medications just don’t work for you because they are too strong. Products that are too strong for you can cause increased inflammation, which can actually lead to more acne rather than less. Because of this, salicylic acid is our number one recommendation for sensitive skin.

Acne vulgaris is the catch-all term for everything from angry red lesions to tiny white bumps, which are the results of hair follicles and their sebaceous glands becoming blocked and inflamed So our first plan was to look at it all — spot treatments, washes, scrubs and creams — until we learned that when it comes to over-the-counter treatments, there is no single cure.
Again, this is another straightforward method but one that is very effective. We use our sense of touch every day of our lives to ascertain the nature of things. Understanding what type of skin you have is also something that your sense of touch can help you with. Oily complexions will leave visible residue on your fingertips, while healthy, fresh skin will feel smooth to the touch.
“You unfortunately cannot determine the strength of a product strictly by the percentage of its active ingredients because how well a product works depends on how well its inactive ingredients help it penetrate the skin,” explains Dr. Green. “In other words, a 2 percent benzoyl peroxide may be more effective than another brand’s 5 percent benzoyl peroxide because there are other ingredients helping out.”
A complete skin care regimen to control acne usually starts with washing. The ideal face wash creates a soft creamy lather in warm water. It rinses off dirt, excess oil, and makeup, leaving the face ready for the next step in daily skin care, whether that is toner, moisturizer, exfoliant, sunblock, or more makeup. It is fragrance-free, and it does not create a foam, film, or tingly sensation on the face. Any product that foams and suds vigorously, like a detergent, is a strict no-no for acne treatment, especially on dry skin.
The healing and sedative effect is provided by the natural ingredients that are included in the composition – manuka honey, aloe vera and variety of botanicals. They increase skin elasticity, allow it to maintain its normal water balance, prevent premature aging of the skin. The gel is recommended for daily use, it does not dry out the skin and does not cause painful irritation.

Sometimes birth control alone isn’t enough to really make a difference in hormonal acne. That’s when your doctor might recommend adding in an androgen blocker such as Spironalactone. Spiro (as it’s called) minimizes the amount of androgen hormones in circulation by blocking the receptors that bind with testosterone. When these pills are taken at the same time as an oral contraceptive, 90 percent of women see an improvement in breakouts, according to Linkner. The drug is sometimes prescribed to women with PCOS (polycystic ovarian syndrome) to relieve androgen-related symptoms like excessive hair growth, hypertension, oily skin, and acne.

The costs and social impact of acne are substantial. In the United States, acne vulgaris is responsible for more than 5 million doctor visits and costs over US$2.5 billion each year in direct costs.[13] Similarly, acne vulgaris is responsible for 3.5 million doctor visits each year in the United Kingdom.[19] Sales for the top ten leading acne treatment brands in the US in 2015, have been reported as amounting to $352 million.[175]

Acrokeratosis paraneoplastica of Bazex Acroosteolysis Bubble hair deformity Disseminate and recurrent infundibulofolliculitis Erosive pustular dermatitis of the scalp Erythromelanosis follicularis faciei et colli Hair casts Hair follicle nevus Intermittent hair–follicle dystrophy Keratosis pilaris atropicans Kinking hair Koenen's tumor Lichen planopilaris Lichen spinulosus Loose anagen syndrome Menkes kinky hair syndrome Monilethrix Parakeratosis pustulosa Pili (Pili annulati Pili bifurcati Pili multigemini Pili pseudoannulati Pili torti) Pityriasis amiantacea Plica neuropathica Poliosis Rubinstein–Taybi syndrome Setleis syndrome Traumatic anserine folliculosis Trichomegaly Trichomycosis axillaris Trichorrhexis (Trichorrhexis invaginata Trichorrhexis nodosa) Trichostasis spinulosa Uncombable hair syndrome Wooly hair Wooly hair nevus
The good news about oily skin is that it is less likely to wrinkle, is more supple and doesn’t show its age as soon as other skin types. The bad news is that pores get clogged with oil more frequently. Using a daily gentle exfoliator can balance your skin’s tone and texture and keep pores unplugged. There are also anti-bacterial exfoliators that can speed up healing for breakouts.
Combination therapy—using medications of different classes together, each with a different mechanism of action—has been demonstrated to be a more efficacious approach to acne treatment than monotherapy.[10][46] The use of topical benzoyl peroxide and antibiotics together has been shown to be more effective than antibiotics alone.[10] Similarly, using a topical retinoid with an antibiotic clears acne lesions faster than the use of antibiotics alone.[10] Frequently used combinations include the following: antibiotic and benzoyl peroxide, antibiotic and topical retinoid, or topical retinoid and benzoyl peroxide.[46] The pairing of benzoyl peroxide with a retinoid is preferred over the combination of a topical antibiotic with a retinoid since both regimens are effective but benzoyl peroxide does not lead to antibiotic resistance.[10]
Acne vulgaris is a chronic skin disease of the pilosebaceous unit and develops due to blockages in the skin's hair follicles. These blockages are thought to occur as a result of the following four abnormal processes: a higher than normal amount of oily sebum production (influenced by androgens), excessive deposition of the protein keratin leading to comedo formation, colonization of the follicle by Propionibacterium acnes (P. acnes) bacteria, and the local release of pro-inflammatory chemicals in the skin.[49]
The main hormonal driver of oily sebum production in the skin is dihydrotestosterone.[1] Another androgenic hormone responsible for increased sebaceous gland activity is DHEA-S. Higher amounts of DHEA-S are secreted during adrenarche (a stage of puberty), and this leads to an increase in sebum production. In a sebum-rich skin environment, the naturally occurring and largely commensal skin bacterium P. acnes readily grows and can cause inflammation within and around the follicle due to activation of the innate immune system.[10] P. acnes triggers skin inflammation in acne by increasing the production of several pro-inflammatory chemical signals (such as IL-1α, IL-8, TNF-α, and LTB4); IL-1α is known to be essential to comedo formation.[44]
“Sometimes I see people try over-the-counter products just for a couple of weeks, they get frustrated, they say it’s not working, and they discontinue them,” Arthur says. “But it really does take a while to see the effectiveness. So unless you’re having a problem with the medication, like it’s causing severe irritation or dryness, it’s recommended to give it at least 2-3 months before switching to something else.”
Genetics play a big part in who gets acne and how severely, but each blemish can be blamed on some combination of sebum production, a bacteria called Propionibacterium acnes (P. acnes), plugged follicles, and inflammation. Finding a good treatment is really about finding the right combination of ingredients to troubleshoot each of those issues. Some factors that might worsen acne include hormones, certain medications, diet and stress.
Although there is no one single cure for acne, we based our reviews first on what doctors are saying about these products and their ingredients. Then we did some digging into all the reviews. We ruled out those products that had primarily negative responses. After all that, we consulted natural product experts to see which system they felt were the best acne treatment.
Acne is not curable, but it is controllable. Proper acne treatment can prevent and/or improve acne scars and help you to feel and look your best. Seeing a dermatologist like Dr. Turner helps ensure that you are getting the best acne treatment available, since she makes outstanding patient care a priority. This means she listens to patients’ concerns and chooses appropriate therapies for each individual. A consultation with Dr. Turner will be comfortable, informative and respectful. To schedule a visit to discuss therapeutic options, you can book an appointment online or call the office to make an appointment at (214) 373-7546.

First, let’s talk about what causes acne. Pimples form when the oil and dead skin cells on your skin combine to form a plug that blocks the pores. “As the P. acnes bacteria that naturally live on skin overgrow within this plugged follicle, the area becomes inflamed and this is when you start to see papules, pustules, and cystic lesions,” RealSelf dermatologist Sejal Shah, M.D., tells SELF. The treatments ahead work to exfoliate away dead skin cells, suck up excess oil, stop inflammation, and kill the P. acnes bacteria. There are even a few treatments that target hormonal acne specifically.
Skin type, tone, and condition vary from person to person. That explains why what worked for your best friend hasn’t helped you at all. If you are at the end of your rope with your acne and find that it is affecting your life, you really should see a dermatologist before struggling to find a new treatment. A dermatologist might still have to try a few different approaches, but they are trained to get through the process quicker. However, if your acne hasn’t caused you serious problems yet, visiting a dermatologist can be a time-consuming and expensive option. This is why many doctors say mild- to moderate- acne can be treated with over-the-counter products.
Meanwhile, salicylic acid, which is derived from willow tree bark, wintergreen oil or sweet birch and occurs naturally in fruits like raspberries, cantaloupe and granny smith apples, works well for most skin types. Aside from being an exfoliant that sloughs away dead skin cells and other pore-clogging impurities, it has anti-inflammatory properties that help to address inflammation, which is thought to be the primary cause of acne.
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This problem is normally located on the face, back, and upper portion of the chest. These areas are worst hit because they have the highest number of oily glands. What a lot of people don’t realize is that there are several different types of this issue. And to make matter even more complicated, each of these types have their own causes and effects as well as methods of prevention. [3]
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Considerations: Ask your doctor before using any other products on your skin while using erythromycin, as it may be too irritating. This includes other prescriptions, over-the-counter medicines (including those listed on this site), and harsh or abrasive cleansers, perfumes, or make-up.2 People report burning as the most frequent side effect, and also peeling, dryness, itching, redness, and oiliness, among others.2
This dermatologist-tested formula is a foaming face wash that works incredibly fast. It can make skin visibly clearer in as little as 12 hours. It’s made with 2% salicylic acid, Acceladerm Technology™, and PHAs, polyhydroxy acids that open pores, improve skin moisturization and calms the skin. It unblocks pores, kills bacteria and calms and soothes the skin. This Clearasil product is guaranteed to be so good that if it doesn’t work for you, they have a 30-day money-back guarantee that you can take them up on.

Tiege Hanley employs a chemist – known only as “The Chemist” – who formulates all of its products. According to TH, The Chemist is a firm believer that diet and excessive face-washing don’t clear up acne  but that a topical treatment makes all the difference. Tiege Hanley’s acne cream is infused with salicylic acid, which helps shed the top layer of skin cells


Frequently used topical retinoids include adapalene, isotretinoin, retinol, tazarotene, and tretinoin.[46] They often cause an initial flare-up of acne and facial flushing, and can cause significant skin irritation. Generally speaking, retinoids increase the skin's sensitivity to sunlight and are therefore recommended for use at night.[1] Tretinoin is the least expensive of the topical retinoids and is the most irritating to the skin, whereas adapalene is the least irritating to the skin but costs significantly more.[1][84] Tazarotene is the most effective and expensive topical retinoid, but is not as well-tolerated.[1][84] Retinol is a form of vitamin A that has similar but milder effects, and is used in many over-the-counter moisturizers and other topical products.
Many different treatments exist for acne. These include alpha hydroxy acid, anti-androgen medications, antibiotics, antiseborrheic medications, azelaic acid, benzoyl peroxide, hormonal treatments, keratolytic soaps, nicotinamide, retinoids, and salicylic acid.[75] They are believed to work in at least four different ways, including the following: reducing inflammation, hormonal manipulation, killing P. acnes, and normalizing skin cell shedding and sebum production in the pore to prevent blockage.[76] Common treatments include topical therapies such as antibiotics, benzoyl peroxide, and retinoids, and systemic therapies including antibiotics, hormonal agents, and oral retinoids.[19][77]

The predisposition to acne for specific individuals is likely explained by a genetic component, a theory which is supported by studies examining the rates of acne among twins and first-degree relatives.[2] Severe acne may be associated with XYY syndrome.[39] Acne susceptibility is likely due to the influence of multiple genes, as the disease does not follow a classic (Mendelian) inheritance pattern. Multiple gene candidates have been proposed including certain variations in tumor necrosis factor-alpha (TNF-alpha), IL-1 alpha, and CYP1A1 genes, among others.[18] Increased risk is associated with the 308 G/A single nucleotide polymorphism variation in the gene for TNF.[40]

Tretinoin: As we said above, tretinoin (common brand name: Retin-A) is a synthetic retinoid, but it is stronger than some of the other options, and its cousin, isotretinoin, is even stronger. Isotretinoin, better known as Accutane, is an oral synthetic retinoid typically only prescribed for very severe cases of cystic acne because it can cause intense side effects and is a powerful teratogen, meaning it causes birth defects. However, after taking isotretinoin for several months, many people never need to do any serious acne treatment again, so for some, it is well worth the side effects.
Stronger cases may call for prescription retinoids (such as Retin-A or Tazorac), which “are really the standard of care for most acne therapy,” says Joshua Zeichner, MD, director of cosmetic and clinical research in dermatology at Mount Sinai Hospital in New York City. Certain drugs, such as Epiduo and Ziana, combine retinoids with antibacterials and may be more effective than separate products. Because retinoids also have anti-wrinkle properties (they help stimulate collagen production), they are especially beneficial for adult acne sufferers.

For some, the right dosage can be found over-the-counter in concentrations as low as 2.5 percent or up to 10 percent, but for others, a prescription dosage is needed to see the best results. Prescription doses rarely go over 10 percent, as benzoyl peroxide is known to cause stinging, burning, itching, flaking, peeling, and redness2 when used in concentrations over 5 percent, but they may combine the benzoyl peroxide with other acne medications.


Comedonal is the mildest type of acne and doesn’t cause painful swelling or inflammation in most cases. It usually manifests as blackheads or whiteheads on the skin. Blackheads occur when dirt and germs under the skin’s pores cause the skin to appear dark. Males going through puberty, as well as young adults, will experience some form of comedonal acne in their lives. It also may occur because of allergic reactions to skin or hair products, but most acne lesions, such as whiteheads and blackheads, occur because of a hard blockage of excess sebum in skin pores.
Ideally, you want to find an acne face wash and care system that utilizes a number of these ingredients, for best results. It can be a full system by a single brand, like Exposed Skin Care, or it can be a combination of products that you’ve tried and tested for yourself. The important thing to take away here is that there are several ways to treat your acne and knowing what each ingredient does will help you tailor the perfect solution for you.
Both salicylic acid and benzoyl acid are commonly found in the top acne treatments for getting rid of mild to severe acne. They work in tandem to getting rid of the dead skin and killing bacteria, which are two of the main contributors to the spread of acne. Salicylic acid breaks up the skin to clear pores from skin, oil and bacteria and benzoyl peroxide kills the bacteria slowly over a 48-hour period.
Whether it’s just or not, you are judged by your appearance: the clothes you wear, your hairstyle, your body language. And if you have acne, life can be more difficult for you. You may feel uncomfortable in social settings. You may lose your confidence. It could destroy intimacy with someone you care about. If your poor self-esteem affects your job performance, then having acne could even have a negative impact on your income and career advancement. There’s no such thing as ‘growing out of acne’. It’s an issue that needs to be taken seriously. The only way to fight acne is by treating it. And to fight acne head-on, you need to find the best acne treatment for you.

PanOxyl Acne Foaming Wash: This product is marketed for facial acne, but we recommend using on pesky body acne instead. PanOxyl uses benzoyl peroxide, a highly effective acne-fighting ingredient that we’ll describe more just below, but at a concentration that is much too high to be used on your face. Most PanOxyl products contain 10% benzoyl peroxide, which will likely cause peeling and burning on your face, but could be the perfect solution for back or butt acne.


Combined oral contraceptives. Four combined oral contraceptives are approved by the FDA for acne therapy in women who also wish to use them for contraception. They are products that combine estrogen and progestin (Ortho Tri-Cyclen, Yaz, others). You may not see the benefit of this treatment for a few months, so using other acne medications with it the first few weeks may help.
Spironolactone has relatively minor side effects, like low appetite, weakness, or cramping, but there’s one major exception: spironolactone comes with a black box warning about its cancer-causing effects. The FDA is required to include this label based on a study conducted in the 1950s that found carcinogenic properties in the spironolactone given to rats in an experiment. However, the dose of spironolactone used in this study was nearly 500 times higher than the dose currently prescribed, and no studies since have found anything carcinogenic about spironolactone. Because of this, most dermatologists feel comfortable prescribing spironolactone for acne. Still, it’s something to be aware of before you take it. Additionally, those with low blood pressure or kidney conditions are likely not good candidates for spironolactone and may want to explore other acne treatment options.
Acne usually improves around the age of 20, but may persist into adulthood.[75] Permanent physical scarring may occur.[19] There is good evidence to support the idea that acne and associated scarring negatively affect a person's psychological state, worsen mood, lower self-esteem, and are associated with a higher risk of anxiety disorders, depression, and suicidal thoughts.[3][30][50] Another psychological complication of acne vulgaris is acne excoriée, which occurs when a person persistently picks and scratches pimples, irrespective of the severity of their acne.[61][155] This can lead to significant scarring, changes in the affected person's skin pigmentation, and a cyclic worsening of the affected person's anxiety about their appearance.[61] Rare complications from acne or its treatment include the formation of pyogenic granulomas, osteoma cutis, and solid facial edema.[156] Early and aggressive treatment of acne is advocated by some in the medical community to reduce the chances of these poor outcomes.[4]

The use of antimicrobial peptides against P. acnes is under investigation as a treatment for acne to overcoming antibiotic resistance.[10] In 2007, the first genome sequencing of a P. acnes bacteriophage (PA6) was reported. The authors proposed applying this research toward development of bacteriophage therapy as an acne treatment in order to overcome the problems associated with long-term antibiotic therapy such as bacterial resistance.[178] Oral and topical probiotics are also being evaluated as treatments for acne.[179] Probiotics have been hypothesized to have therapeutic effects for those affected by acne due to their ability to decrease skin inflammation and improve skin moisture by increasing the skin's ceramide content.[179] As of 2014, studies examining the effects of probiotics on acne in humans were limited.[179]
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Most studies of acne drugs have involved people 12 years of age or older. Increasingly, younger children are getting acne as well. In one study of 365 girls ages 9 to 10, 78 percent of them had acne lesions. If your child has acne, consider consulting a pediatric dermatologist. Ask about drugs to avoid in children, appropriate doses, drug interactions, side effects, and how treatment may affect a child's growth and development.
Benzoyl peroxide is one of the most popular acne medications available, and it works especially well for pimples because it kills the bacteria that causes them. It works by bringing oxygen under the skin, killing the particular type of bacteria associated with acne, known as p. acnes. P. acnes are anaerobic, meaning they can’t live where there is oxygen, so benzoyl peroxide is a great way to kill bacteria under the skin instantaneously1. This medication can often eradicate acne if used in the right dosage and in the right way.
Acne is the most common skin condition in the United States. Between 40 and 50 million Americans have it. It occurs at any age, but most sufferers are teenagers and young adults. Research shows four key players are involved in its formation: excess oil, clogged pores, bacteria and inflammation. The excess oil is sebum which our bodies make to prevent the skin from drying out. Sebum increases dramatically during adolescence when hormones known as androgens spur sebum production into overdrive. If excess sebum cannot flow freely to the skin’s surface, clogged pores result. P. acnes, a bacteria found on everyone’s skin, flourishes in the excess oil and results in inflammation.
Acne removal: Your dermatologist may perform a procedure called “drainage and extraction” to remove a large acne cyst. This procedure helps when the cyst does not respond to medicine. It also helps ease the pain and the chance that the cyst will leave a scar. If you absolutely have to get rid of a cyst quickly, your dermatologist may inject the cyst with medicine.
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